Erythromycin Lactobionate 1g Powder for Solution for Infusion – Summary of Product Characteristics (SmPC) by ADVANZ Pharma. Erythromycin Lactobionate I.V. is a sterile presentation of erythromycin. It is not When administering the product by intermittent infusion do not use solution strengths greater than . includes any possible side effects not listed in this leaflet. Intravenous infusion of mg of erythromycin lactobionate at a constant rate physiologically concentrated or in situations where high dosage of drug can be.

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There have been reports of infantile hypertrophic pyloric stenosis IHPS occurring in infants following erythromycin therapy. Erythrocin Lactobionate Rating No reviews – Add your review. Use Erythromycin Lactobionate – I. The induction decreases gradually during two weeks after discontinued treatment with CYP3A4 inducers. Erythromycin is excreted principally by the liver, so caution should be exercised in administering alctobionate antibiotic to patients with impaired hepatic function or concomitantly receiving potentially hepatotoxic agents.

Erythromycin is contraindicated in patients taking simvastatin, tolterodine, mizolastine, amisulpride, astemizole, terfenadine, domperidone, cisapride or pimozide.

Erythromycin Lactobionate 1g Powder for Solution for Infusion

Erythromycin is usually active against most strains of the following organisms both in vitro and in clinical infections: Cimetidine may inhibit the metabolism of erythromycin which may lead to an increased plasma concentration. Intravenous erythromycin should be replaced by oral erythromycin as soon as possible. Erythromycin significantly alters the metabolism of terfenadine, astemizole and pimozide when taken concomitantly.


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There have been post-marketing reports of colchicine toxicity with concomitant use of erythromycin and colchicine. Particular care should lacttobionate taken with medications known to prolong the QTc interval of the electrocardiogram. Since erythromycin may be used in the treatment of conditions in infants which are associated with significant mortality or morbidity such as pertussis or chlamydiathe benefit of erythromycin therapy needs to be weighed against the potential risk of developing IHPS.

Following intravenous infusion, erythromycin is widely distributed throughout body tissues, including lung tissues. Recommended Administration Bolus injection IV push is contraindicated Continuous infusion of this medicine is preferred due to the slower infusion rate and lower concentration of erythromycin; however, intermittent infusion at intervals not greater than every six hours is also effective. Investigations Increased liver enzyme values. Lzctobionate infant birth to 1 month: Medically reviewed on Sep 5, This site uses cookies.

The majority of strains of Haemophilus influenzae are pacage to the concentrations reached after ordinary doses.

Erythromycin Lactobionate – I.V. Information –

Erythromycin exerts its antimicrobial action by binding to the 50S ribosomal sub-unit of susceptible microorganisms and suppresses protein synthesis. Glass vial with rubber closure. CDAD must be considered in all patients who present with diarrhoea following antibiotic use. Erythromycin is contraindicated with ergotamine and dihydroergotamine. We comply with the HONcode standard for trustworthy health information – verify here.


This may lead to paackage levels of erythromycin and a decreased effect.

Erythromycin Lactobionate – I.V.

There have been reports suggesting erythromycin does not reach the foetus in adequate concentrations to prevent congenital syphilis. If you think there has been an overdose, call your poison control center or get medical care right away.

Bronchitis ciprofloxacinamoxicillindoxycyclineazithromycinAugmentinMore Bolus injection IV push is an unacceptable route of administration. By continuing to browse the site you are agreeing to our policy on the use of cookies.

Step 1 – add 20 ml erythromycni Water for Injections BP to the 1 g vial. For Continuous Infusion of 1 gram dose: If you have questions about side effects, call your doctor.

All drugs may cause side effects. Chest pain, fever, malaise.