Fundamental principles of bhaishajya kalpana. The word Bhaishajya Kalpana is composed of two words – Bhaishajya and Kalpana. The word. Bhaishjya kalpana deals with the Basic Ayurvedic pharmaceutics. •The first systematic knowledge of Bhaishajya Kalpana is found in Caraka. Doctor of Medicine in Rasashastra & Bhaishajya Kalpana (Medicinal Chemistry and Pharmacy) is Non – Clinical course. Keeping with tradition, the course.

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Different aspects of their preparation and use have been discussed. Further, Ayurvedic classics also give emphasis to the elimination of inherent constituents of the drug which are inappropriate in specific clinical condition and toxic in nature and which enter into the formulation if not removed.

The paste is then rolled into a bolus which is wrapped in the coverings of leaves. These are shown in Table 2. Khara paaka rough consistency oil is used for bathing. This was taken care by devising appropriate dosage forms.

It is possible that because of the ecological conditions prevailing in different parts from where the material is procured ,alpana same material collected from different regions may not have same kalpan profile. The supernatant liquid is decanted and the remaining Sattva is washed with water and decanted and the process is repeated several times.

The Sattva so sedimented is allowed to dry and is powdered. If required liquids like milk, ghee butter oiloil, cow urine in the measure of 10 ml.

Studies carried out in our Institute have shown that many other factors like use of cultivated raw material or naturally collected material, processing methods like murchanaa, sodhana, avartana, bhaiishajya of putas method of heating while preparing a bhasma all have influence over expression of pharmacological activity.

Not all but some of the plant ingredients are therapeutically active. Additives such as cumin seeds, gum guggulu, caustic substances, salt, asphalt, asafoetida, mixture of ginger, black and long pepper in the measure of 3 g each are added as per requirement. Many a times the place or source of materials especially of adjuvants and vehicles is not specified. In all these cases one fourth part of water is retained after boiling.

The results obtained indicate in many cases adjuvant used may not be inert but per se may produce significant pharmacological activities. In one of the studies carried out in our lab Savrikar, three samples of guduchi ghritas were prepared using cow ghee ghrita obtained from three different regions- Wardha, Nanded and Solapur and the samples were evaluated for bjaishajya pharmacological activities.


Plant, bhaishajha or mineral product in whatever nature they may be they can be hardly used as a drug in their natural form.

Hence while making changes in the classical formulation this point should be noted and changes should not be made without valid reasons. When no Anupana is specified such oil should kapana taken with warm water or warm milk Vhaishajya, The plant ingredients are dried and made into fine powders, separately and ground to soft pastes before they are rolled in to pills with the help of fingers.

The information related to drugs and formulations along with diagnosis and management of disease accompanied with techniques of health maintenance through observance of proper daily and seasonal routines bhaisuajya be found in large number of classical and other literary works.

Shri Ayurved Mahavidyalaya

Differences in the activity profile was observed. In one of the studies it has been shown that season of collection byaishajya raw drugs can influence the expression of pharmacological activity Sridhara Bairy, Comparative Pharmaco-clinical study on Panchtikta ghrita prepared by different methods in Ekakustha Psoriasis M. Vati and Gutikas – drug forms prepared in the form of tablet or pills.

Formulation factors influencing expression of pharmacological activity Though it is generally accepted among the ayurvedic fraternity that drug formulation kalpanx very important for ensuring therapeutic efficacy, not much importance is being given to assess or ascertain the impact of changes made in formulation factors on the expression of pharmacological activity. Dosage form Brief description Basti Per rectal administration of medicated oils and emulsions Guda varti Per rectal insertion of suppository Uttar Basti Per-urethral, per-vaginal administration of medicated oils and emulsions Nasya Nasal instillation and inhalations nasal insufflations Aschyotana Eye drops Anjana Eye creams and ointments Karnapurana Ear drops Ksaara a sutra Surgical thread coated with caustic or acrid drug material.

It is apparent that the expected plant ingredients having specific therapeutic action of above mentioned plants will be destroyed if other procedures of kalpaan are utilized because of the sensitive nature of the related plant ingredients. This is then made into thin sticks of about 2 centimeters in length and dried in shade. Vegetable lepa coorna powder will preserve their potency for 30 days if bnaishajya in air tight containers. The contents are then subjected to heating to retain one fourth of the water.


The observed effect was compared against a water control group. A Comparative Pharmaco-clinical study of Churna, Ghrita and Sharkara of Yashti-madhu in Parinama-shool with special reference to duodenal ulcer.

Since the plant material used for drug preparation is very similar to food material the cooking practices such as heating, boiling, frying etc. Thesis submitted to Gujarat Ayurved University, Jamnagar.

Bhaishajya Kalpanaa – The Ayurvedic Pharmaceutics – An Overview

The third part of the review is devoted to discussion of influence of different factors on the expression of pharmacological activity. However, two of the varieties, namely Mahisa a ksha and Kanaka Guggulu are usually preferred for medicinal preparations.

In case of formulations in which minerals are used, the drugs are preserved for indefinite period. A detailed account of different stable dosage forms is given by the classics.

In Ayurvedic therapeutics, drugs in both forms are used, crude as well as processed and converted into different formulations.

Bhaishajya Kalpanaa – The Ayurvedic Pharmaceutics – An Overview

When the mass is properly ground and is in a condition to be made into pills- flavoring agents are added and ground again. Author information Copyright and License information Disclaimer. GuduciHolarrhena antidysenterica Linn. It is obtained by boiling the finely powdered plant material in required quantity of water till all the active ingredients are extracted completely in kalapna water.

They are put to use depending upon the condition of the patient with respect to his digestive capability e. Significant decrease in ulcer index was observed in Yasti ghrita administered group; in other two groups only moderate and statistically non-significant decrease was observed. Water, Cow’s urine, oil, and ghee ghaishajya some of the media used for mixing. Apart from this the following plants should be used only till they retain their natural bhaisbajya