The purpose of the study is to evaluate the physical performance of a Biograph mCT Flow R PET/CT system (Siemens Healthcare, Germany) and to. to fundamentally change how PET imaging is performed. Powered by Siemens’ revolutionary FlowMotion™ technology,. Biograph mCT Flow™ is the world’s first. Biograph mCT Flow with FlowMotion™ technology combines our standard- setting PET/CT with a unique system design that enables continuous motion of.

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The axial end slices first and last slice were excluded from the analysis. Axial sensitivity profile for the measurements with the line source in the center of the field of view and at cm radial offset. For this acquisition protocol, planning and scanning are restricted by the fixed size of the detector array.

This information can be used to significantly improve the image signal-to-noise ratio SNR of the reconstructed PET images, thus, allowing for better image quality and shorter acquisition times [ 89 ]. The sphere-to-background ratio is 8: In a study by Tong et al.

Lesion detectability depends on the acquisition time [ 31 ]. The measured sensitivity was 9. Seminars in Nuclear Medicine. The axial sensitivity biobraph with the line source placed at the center of the FOV and cm mft offset are shown in Fig. The line source was filled with an initial activity of 1. The CTM acquisition followed biogeaph sequential subsequently.

All measurements were performed at the site of the biogrraph installation of the system between August and December Previous studies have shown that by incorporating PSF modeling into the image reconstruction, an overestimation of the CRC can be observed, in particular, when no post-filtering is applied [ 252829 ]. Regarding the IQ test, the only difference between the and standard is a reduction of emission scan time by a factor of 2.


The CTM scans were acquired with a table speed of bigoraph. No attenuation and scatter correction and no post-smoothing filter were applied. Conclusions The spatial resolution, sensitivity, scatter fraction, and count rates were in concordance with the published values for the predecessor system, the Biograph mCT.

Nonetheless, here, the patient handling system had a sufficient vertical table range and the line sources were filled to meet exactly the mm in-tube filling, and, therefore, these changes were not applicable to our measurements.

Please review our privacy biograp. For resolution measurements, an 18 F point source inside a glass capillary tube was used.

Received Jun 15; Accepted Oct Image quality phantom hot spheres at the center of the axial FOV The calculated activities at the start of the second scan were 5.

Image quality is very similar. Discussion Our data indicate a similar performance of the PET components of the mCT Flow and its predecessor system, the mCT [ 6 ] with the residual differences being discussed below.

National Center for Biotechnology InformationU. Nevertheless, based on the findings of Molina-Duran and colleges, [ 33 ] not the entire increase in BG variability can be explained from the decrease in count density. Based on this relationship, a considerable decrease in detectability is expected when the acquisition time is reduced by a factor of 2, which is inevitably related to image contrast.

The scatter fraction and NECR were determined as described in the NEMA NU standard [ 19 ] acquired using software tools provided by the manufacturer and evaluated using in-house software. The average and range percent contrast obtained for hot and cold spheres, the average and range standard deviation of the background counts, and the mean residual error in scatter and attenuation corrections were evaluated.


Biograph mCT for Radiation Oncology – Siemens Healthineers Global

The count rate error evaluation was also slightly modified in the standard. Open in a separate window. Healthcare Siemens White Paper. Therefore, the CTM acquisitions resulted in a lower number of collected true events than in SS mode, which in turn resulted in an elevated background variability ,ct 33 ].

Biograph mCT Flow

In this study, the IQ phantom images were acquired with a table speed of 0. The bladder was jct to test for this issue as it contains a uniform activity concentration and therefore similar to the background compartment in the IQ phantom.

The most significant difference between both standards is the change of the positions of the point source for spatial resolution measurements. When the effects of post-filtering and acquisition duration are taken into account, the values measured in this study show a closer conformance to those previously published [ 6 ]. A second scan of the same region in CTM mode was acquired at a table speed biovraph 0. Therefore, it is suggested to define a set of parameters iterations, subsets, post-filtering, and algorithm for each system for a standardized evaluation of the image quality.

Fully 3-D PET reconstruction with system matrix derived from point source measurements. The evaluation of positron emission tomographs requires reproducible and reliable methods to allow the comparison of different systems using accepted measurement standards.

Methods for improving image quality in whole body PET scanning. No noticeable differences were found between the two systems.